Cytokines in Chronic Hepatitis C Liver Diseases: Interleukin 20

Interleukin-1 Family Cytokines in Liver Diseases

The gene encoding IL-1 was sequenced more than 30 years ago, and many related cytokines, such as IL-18, IL-33, IL-36, IL-37, IL-38, IL-1 receptor antagonist (IL-1Ra), and IL-36Ra, have since been identified. IL-1 is a potent proinflammatory cytokine and is involved in various inflammatory diseases. Other IL-1 family ligands are critical for the development of diverse diseases, including inflamm...

Cytokines in Chronic Neurodegenerative Diseases

Cytokines in chronic respiratory diseases

Cytokines are small, secreted proteins that control immune responses. Within the lung, they can control host responses to injuries or infection, resulting in clearance of the insult, repair of lung tissue, and return to homeostasis. Problems can arise when this response is over exuberant and/or cytokine production becomes dysregulated. In such cases, chronic and repeated inflammatory reactions ...

Non Alcoholic Fatty Liver Diseases in Chronic Hepatitis C: Impact on End Treatment Virologic Response

Background: Both nonalcoholic fatty liver disease (NAFLD) and chronic hepatitis C (CHC) are frequent causes of chronic liver disease. Questions remain regarding the etiology of steatosis and steatohepatitis in hepatitis C, and its impact on disease progression and treatment outcomes. Objectives: To estimate the association of NAFLD with CHC and to evaluate the effect of steatosis and non alcoho...

Liver biopsy in chronic hepatitis C: the experience of 15 Italian wards of infectious diseases.

To evaluate the impact of liver histology on the management of HCV-related chronic hepatitis, 281 patients with chronic HCV infection who consecutively underwent percutaneous liver biopsy (LB) at one of the 15 participating Italian Units of Infectious Diseases were investigated in 2005. Demographic, aetiological, laboratory and clinical data and information on methods applied to perform ultraso...